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Pfizer Inc
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ActivX Inc
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ASINEX Inc
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Image Search Results
Journal: Cold Spring Harbor Perspectives in Medicine
Article Title: Antibacterial Drug Discovery Targeting the Lipopolysaccharide Biosynthetic Enzyme LpxC
doi: 10.1101/cshperspect.a025304
Figure Lengend Snippet: LpxC inhibitors. Merck: L-573,655 (compound 1) and L-161,240 (compound 2) (Onishi et al. 1996; Chen et al. 1999). British Biotech (Oxford): BB-78485 (compound 3) (Clements et al. 2002). University of Washington (UW)/Chiron (Emeryville, CA): compounds 4 and 5, previously designated 26 and 69 (Kline et al. 2002); compounds 6–10 (Andersen et al. 2011). In publications characterizing UW/Chiron compounds 7–10, they have been designated Lpc-004, CHIR-090, Lpc-009, and Lpc-011, respectively (McClerren et al. 2005; Lee et al. 2011; Liang et al. 2011). Pfizer (New York): LpxC-4 (PF-5081090) (compound 11) (Tomaras et al. 2014), previously compound 17-v (Montgomery et al. 2012), and PF1090 (Bulitta et al. 2011). Achaogen (South San Francisco): ACHN-975 (compound 12) (Kasar et al. 2012; Serio et al. 2013).
Article Snippet: A press release dated December 22, 2015 from
Techniques:
Journal: Cold Spring Harbor Perspectives in Medicine
Article Title: Antibacterial Drug Discovery Targeting the Lipopolysaccharide Biosynthetic Enzyme LpxC
doi: 10.1101/cshperspect.a025304
Figure Lengend Snippet: Susceptibility of E. coli to LpxC inhibitors is dependent on the source of lpxC gene
Article Snippet: A press release dated December 22, 2015 from
Techniques: