lpxc inhibitors Search Results


90
Forge Therapeutics lpxc inhibitors
Lpxc Inhibitors, supplied by Forge Therapeutics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Achaogen Inc n-acetylglucosamine deacetylase (lpxc) inhibitor gsk-214094b
N Acetylglucosamine Deacetylase (Lpxc) Inhibitor Gsk 214094b, supplied by Achaogen Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Axon Medchem LLC lpxc inhibitors pf-05081090
Lpxc Inhibitors Pf 05081090, supplied by Axon Medchem LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Forge Therapeutics nonhydroxamate lpxc inhibitor
<t>LpxC</t> inhibitors. Merck: L-573,655 (compound 1) and L-161,240 (compound 2) (Onishi et al. 1996; Chen et al. 1999). British Biotech (Oxford): BB-78485 (compound 3) (Clements et al. 2002). University of Washington (UW)/Chiron (Emeryville, CA): compounds 4 and 5, previously designated 26 and 69 (Kline et al. 2002); compounds 6–10 (Andersen et al. 2011). In publications characterizing UW/Chiron compounds 7–10, they have been designated Lpc-004, CHIR-090, Lpc-009, and Lpc-011, respectively (McClerren et al. 2005; Lee et al. 2011; Liang et al. 2011). Pfizer (New York): LpxC-4 (PF-5081090) (compound 11) (Tomaras et al. 2014), previously compound 17-v (Montgomery et al. 2012), and PF1090 (Bulitta et al. 2011). Achaogen (South San Francisco): ACHN-975 (compound 12) (Kasar et al. 2012; Serio et al. 2013).
Nonhydroxamate Lpxc Inhibitor, supplied by Forge Therapeutics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/lpxc+inhibitors/nonhydroxamate+lpxc+inhibitor/pmc04930914-162-14-8
Average 90 stars, based on 1 article reviews
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Axon Medchem LLC lpxc inhibitors pf-4753299
<t>LpxC</t> inhibitors. Merck: L-573,655 (compound 1) and L-161,240 (compound 2) (Onishi et al. 1996; Chen et al. 1999). British Biotech (Oxford): BB-78485 (compound 3) (Clements et al. 2002). University of Washington (UW)/Chiron (Emeryville, CA): compounds 4 and 5, previously designated 26 and 69 (Kline et al. 2002); compounds 6–10 (Andersen et al. 2011). In publications characterizing UW/Chiron compounds 7–10, they have been designated Lpc-004, CHIR-090, Lpc-009, and Lpc-011, respectively (McClerren et al. 2005; Lee et al. 2011; Liang et al. 2011). Pfizer (New York): LpxC-4 (PF-5081090) (compound 11) (Tomaras et al. 2014), previously compound 17-v (Montgomery et al. 2012), and PF1090 (Bulitta et al. 2011). Achaogen (South San Francisco): ACHN-975 (compound 12) (Kasar et al. 2012; Serio et al. 2013).
Lpxc Inhibitors Pf 4753299, supplied by Axon Medchem LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/lpxc+inhibitors/lpxc+inhibitors+pf+4753299/pmc08160660-78-5-15
Average 90 stars, based on 1 article reviews
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86
Pfizer Inc methylsulfone hydroxamic acid lpxc inhibitors
<t>LpxC</t> inhibitors. Merck: L-573,655 (compound 1) and L-161,240 (compound 2) (Onishi et al. 1996; Chen et al. 1999). British Biotech (Oxford): BB-78485 (compound 3) (Clements et al. 2002). University of Washington (UW)/Chiron (Emeryville, CA): compounds 4 and 5, previously designated 26 and 69 (Kline et al. 2002); compounds 6–10 (Andersen et al. 2011). In publications characterizing UW/Chiron compounds 7–10, they have been designated Lpc-004, CHIR-090, Lpc-009, and Lpc-011, respectively (McClerren et al. 2005; Lee et al. 2011; Liang et al. 2011). Pfizer (New York): LpxC-4 (PF-5081090) (compound 11) (Tomaras et al. 2014), previously compound 17-v (Montgomery et al. 2012), and PF1090 (Bulitta et al. 2011). Achaogen (South San Francisco): ACHN-975 (compound 12) (Kasar et al. 2012; Serio et al. 2013).
Methylsulfone Hydroxamic Acid Lpxc Inhibitors, supplied by Pfizer Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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90
Taisho Toyama Pharmaceutical Co lpxc inhibitors
<t>LpxC</t> inhibitors. Merck: L-573,655 (compound 1) and L-161,240 (compound 2) (Onishi et al. 1996; Chen et al. 1999). British Biotech (Oxford): BB-78485 (compound 3) (Clements et al. 2002). University of Washington (UW)/Chiron (Emeryville, CA): compounds 4 and 5, previously designated 26 and 69 (Kline et al. 2002); compounds 6–10 (Andersen et al. 2011). In publications characterizing UW/Chiron compounds 7–10, they have been designated Lpc-004, CHIR-090, Lpc-009, and Lpc-011, respectively (McClerren et al. 2005; Lee et al. 2011; Liang et al. 2011). Pfizer (New York): LpxC-4 (PF-5081090) (compound 11) (Tomaras et al. 2014), previously compound 17-v (Montgomery et al. 2012), and PF1090 (Bulitta et al. 2011). Achaogen (South San Francisco): ACHN-975 (compound 12) (Kasar et al. 2012; Serio et al. 2013).
Lpxc Inhibitors, supplied by Taisho Toyama Pharmaceutical Co, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/lpxc+inhibitors/lpxc+inhibitors/pm24354981-242-4-13
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ActivX Inc sulfonamide-based non-alkyne lpxc inhibitors
<t>LpxC</t> inhibitors. Merck: L-573,655 (compound 1) and L-161,240 (compound 2) (Onishi et al. 1996; Chen et al. 1999). British Biotech (Oxford): BB-78485 (compound 3) (Clements et al. 2002). University of Washington (UW)/Chiron (Emeryville, CA): compounds 4 and 5, previously designated 26 and 69 (Kline et al. 2002); compounds 6–10 (Andersen et al. 2011). In publications characterizing UW/Chiron compounds 7–10, they have been designated Lpc-004, CHIR-090, Lpc-009, and Lpc-011, respectively (McClerren et al. 2005; Lee et al. 2011; Liang et al. 2011). Pfizer (New York): LpxC-4 (PF-5081090) (compound 11) (Tomaras et al. 2014), previously compound 17-v (Montgomery et al. 2012), and PF1090 (Bulitta et al. 2011). Achaogen (South San Francisco): ACHN-975 (compound 12) (Kasar et al. 2012; Serio et al. 2013).
Sulfonamide Based Non Alkyne Lpxc Inhibitors, supplied by ActivX Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/lpxc+inhibitors/sulfonamide+based+non+alkyne+lpxc+inhibitors/pm28082037-7-0-32
Average 90 stars, based on 1 article reviews
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Forge Therapeutics lpxc inhibitor discovery program
<t>LpxC</t> inhibitors. Merck: L-573,655 (compound 1) and L-161,240 (compound 2) (Onishi et al. 1996; Chen et al. 1999). British Biotech (Oxford): BB-78485 (compound 3) (Clements et al. 2002). University of Washington (UW)/Chiron (Emeryville, CA): compounds 4 and 5, previously designated 26 and 69 (Kline et al. 2002); compounds 6–10 (Andersen et al. 2011). In publications characterizing UW/Chiron compounds 7–10, they have been designated Lpc-004, CHIR-090, Lpc-009, and Lpc-011, respectively (McClerren et al. 2005; Lee et al. 2011; Liang et al. 2011). Pfizer (New York): LpxC-4 (PF-5081090) (compound 11) (Tomaras et al. 2014), previously compound 17-v (Montgomery et al. 2012), and PF1090 (Bulitta et al. 2011). Achaogen (South San Francisco): ACHN-975 (compound 12) (Kasar et al. 2012; Serio et al. 2013).
Lpxc Inhibitor Discovery Program, supplied by Forge Therapeutics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/lpxc+inhibitors/lpxc+inhibitor+discovery+program/pm32557306-22-34-30
Average 90 stars, based on 1 article reviews
lpxc inhibitor discovery program - by Bioz Stars, 2026-09
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ASINEX Inc lpxc inhibitor bb-78485
<t>LpxC</t> inhibitors. Merck: L-573,655 (compound 1) and L-161,240 (compound 2) (Onishi et al. 1996; Chen et al. 1999). British Biotech (Oxford): BB-78485 (compound 3) (Clements et al. 2002). University of Washington (UW)/Chiron (Emeryville, CA): compounds 4 and 5, previously designated 26 and 69 (Kline et al. 2002); compounds 6–10 (Andersen et al. 2011). In publications characterizing UW/Chiron compounds 7–10, they have been designated Lpc-004, CHIR-090, Lpc-009, and Lpc-011, respectively (McClerren et al. 2005; Lee et al. 2011; Liang et al. 2011). Pfizer (New York): LpxC-4 (PF-5081090) (compound 11) (Tomaras et al. 2014), previously compound 17-v (Montgomery et al. 2012), and PF1090 (Bulitta et al. 2011). Achaogen (South San Francisco): ACHN-975 (compound 12) (Kasar et al. 2012; Serio et al. 2013).
Lpxc Inhibitor Bb 78485, supplied by ASINEX Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/lpxc+inhibitors/lpxc+inhibitor+bb+78485/pm23383626-87-1-39
Average 90 stars, based on 1 article reviews
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86
Merck & Co lpxc inhibitors
<t>LpxC</t> inhibitors. Merck: L-573,655 (compound 1) and L-161,240 (compound 2) (Onishi et al. 1996; Chen et al. 1999). British Biotech (Oxford): BB-78485 (compound 3) (Clements et al. 2002). University of Washington (UW)/Chiron (Emeryville, CA): compounds 4 and 5, previously designated 26 and 69 (Kline et al. 2002); compounds 6–10 (Andersen et al. 2011). In publications characterizing UW/Chiron compounds 7–10, they have been designated Lpc-004, CHIR-090, Lpc-009, and Lpc-011, respectively (McClerren et al. 2005; Lee et al. 2011; Liang et al. 2011). Pfizer (New York): LpxC-4 (PF-5081090) (compound 11) (Tomaras et al. 2014), previously compound 17-v (Montgomery et al. 2012), and PF1090 (Bulitta et al. 2011). Achaogen (South San Francisco): ACHN-975 (compound 12) (Kasar et al. 2012; Serio et al. 2013).
Lpxc Inhibitors, supplied by Merck & Co, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/lpxc+inhibitors/inhibitors+lpxc/pmc12709365-291-11-3
Average 86 stars, based on 1 article reviews
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Image Search Results


LpxC inhibitors. Merck: L-573,655 (compound 1) and L-161,240 (compound 2) (Onishi et al. 1996; Chen et al. 1999). British Biotech (Oxford): BB-78485 (compound 3) (Clements et al. 2002). University of Washington (UW)/Chiron (Emeryville, CA): compounds 4 and 5, previously designated 26 and 69 (Kline et al. 2002); compounds 6–10 (Andersen et al. 2011). In publications characterizing UW/Chiron compounds 7–10, they have been designated Lpc-004, CHIR-090, Lpc-009, and Lpc-011, respectively (McClerren et al. 2005; Lee et al. 2011; Liang et al. 2011). Pfizer (New York): LpxC-4 (PF-5081090) (compound 11) (Tomaras et al. 2014), previously compound 17-v (Montgomery et al. 2012), and PF1090 (Bulitta et al. 2011). Achaogen (South San Francisco): ACHN-975 (compound 12) (Kasar et al. 2012; Serio et al. 2013).

Journal: Cold Spring Harbor Perspectives in Medicine

Article Title: Antibacterial Drug Discovery Targeting the Lipopolysaccharide Biosynthetic Enzyme LpxC

doi: 10.1101/cshperspect.a025304

Figure Lengend Snippet: LpxC inhibitors. Merck: L-573,655 (compound 1) and L-161,240 (compound 2) (Onishi et al. 1996; Chen et al. 1999). British Biotech (Oxford): BB-78485 (compound 3) (Clements et al. 2002). University of Washington (UW)/Chiron (Emeryville, CA): compounds 4 and 5, previously designated 26 and 69 (Kline et al. 2002); compounds 6–10 (Andersen et al. 2011). In publications characterizing UW/Chiron compounds 7–10, they have been designated Lpc-004, CHIR-090, Lpc-009, and Lpc-011, respectively (McClerren et al. 2005; Lee et al. 2011; Liang et al. 2011). Pfizer (New York): LpxC-4 (PF-5081090) (compound 11) (Tomaras et al. 2014), previously compound 17-v (Montgomery et al. 2012), and PF1090 (Bulitta et al. 2011). Achaogen (South San Francisco): ACHN-975 (compound 12) (Kasar et al. 2012; Serio et al. 2013).

Article Snippet: A press release dated December 22, 2015 from Forge Therapeutics (www.forgetherapeutics.com/news-articles) referred to a nonhydroxamate LpxC inhibitor from the same researchers as efficacious in experimental bacterial infections.

Techniques:

Susceptibility of E. coli to  LpxC  inhibitors is dependent on the source of lpxC gene

Journal: Cold Spring Harbor Perspectives in Medicine

Article Title: Antibacterial Drug Discovery Targeting the Lipopolysaccharide Biosynthetic Enzyme LpxC

doi: 10.1101/cshperspect.a025304

Figure Lengend Snippet: Susceptibility of E. coli to LpxC inhibitors is dependent on the source of lpxC gene

Article Snippet: A press release dated December 22, 2015 from Forge Therapeutics (www.forgetherapeutics.com/news-articles) referred to a nonhydroxamate LpxC inhibitor from the same researchers as efficacious in experimental bacterial infections.

Techniques: